Purpose: To report visual and anatomical outcome of flap LOSS after LASIK surgery for correction of high myopia. Materials & Methods: Retrospective evaluation of flap LOSS in two eyes of two patients, a rare complication of LASIK Surgery. Case No. 1: 27 y/o woman with Ref. OD -9.75; 2.75*177 VA. CC: 20/60 KR OD: 41.86*77 39.86 * 168 & partial amblyopia due to anisometropia. Case No. 2: 38 y/o woman with Ref OD. -9.50 1.0*177 VA CC: 20/30 KR OD: 42.06*77 40.99 * 167. Results: In both patients during LASIK surgery free cap complication occurred and after Laser therapy free cap positioned over the stromal bed, but the next day after operation flaps were lost. For case NO.1only medical management performed and after 4.5 years F/U cornea has 2° central haziness. For case NO.2 another corneal flap from donor globe cut and sutured with Nylon 10/0 and after 18 months F/U cornea is clear. Conclusion: In patients with flat keratometry less than 41.0 Diopter rate of free cap are high and after laser therapy for high myopia the keratometry became more flat. If surgeon doesn't suture flap the rate of flap LOSS increase so for prevent of corneal haziness and corneal ectazia this evaluation suppose to perform donor corneal flap graft.      

Aim and Background: Several methods have been applied for reduction of bleeding during the surgery. As vasopressin constricts the vessels and affects the coagulation system, it may reduce bleeding during the operation. The aim of this study was to evaluate the systemic administration of vasopressin on reduction of bleeding during hip arthroplasty.Methods and Materials: In this clinical trial patients scheduled for hip arthroplasty under regional anesthesia, were randomly allocated to two groups, one group received 0.01 unit per minute vasopressin and isotonic saline was administered for the control group, respectively. The patients’ data regarding the amount of blood units transfused and hemoglobin, hematocrit and platelet changes were recruited. After statistical analysis, the effect of vasopressin on reduction of bleeding was evaluated.Findings: The changes in hematocrit and platelet count and transfused blood units were not significantly different between the two groups. After controlling for demographic data and duration of surgery in multiple regression analysis, vasopressin infusion did not change outcome measures.Conclusions: Vasopressin administration has no effect on the reduction of bleeding during hip arthroplasty. The duration of surgery is the onlypredictive factor for the amount of bleeding.

Sarcopenia, the age-related decline in skeletal muscle MASS and function, is one of the main contributors to morbidity and physical disability (1). In women, menopause may contribute to sarcopenia, which not only affects very old wom-en but can also have impact on middle-aged adults (2). Changes in the gonadal hormones dur-ing the menopause transition appear to be a strong determinant of skeletal muscle MASS in women. . . .

Background: One of the most common visceral cancers among men in the world is prostate cancer. Screening for early detection has a positive effect on patients’ survival time. Measurement of serum level of TOTAL PSA and free PSA is abundantly used for screening and diagnosis of prostate cancer. However, no study has been done to determine the relation between serum level of TOTAL PSA and free PSA/TOTAL PSA ratio with malignancy degree on biopsy samples. The aim of this study was to determine the relation of serum level of TOTAL PSA and free PSA/TOTAL PSA ratio, with malignancy degree.Methods: This is a cross-sectional study done in Alzahra Hospital during 2012-2013. We selected 85 patients with prostate cancer whose disease was detected in the pathology ward. Serum level of TOTAL PSA and free PSA were measured, and the degree of malignancy was determined by pathology ward based on the Gleason scoring system. All data was recorded in the questionnaire and entered into the computer and analyzed by SPSS software.Findings: The results of this study showed that there is 38% correlation between Gleason score and free PSA/TOTAL PSA ratio. Based on the Pearson correlation, this relation was statistically significant (P=0.037). Moreover, there is a 37% relation between serum level of TOTAL PSA and the Gleason score; this relation was statistically significant (P<0.001).Conclusion: Prostate cancer is usually detected late and biopsy is rarely accepted by patients. Moreover, serum level of TOTAL PSA and TOTAL PSA/free PSA ratio has a relation with degree of malignancy. Therefore, serum level of PSA can help patients and physicians in early detection and treatment of prostate cancer.